Do not take extra medicine to make up the missed dose. When flying, never put it into a checked bag. They also reduce the amount of cholesterol and triglycerides moving through the body. Before taking this medicine, tell your doctor if you have ever had liver or kidney disease, diabetes, or a thyroid disorder, if you are of Chinese descent, or if you drink more than 2 alcoholic beverages daily. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. This information is not a substitute for medical advice. Never take this medicine in larger amounts, or for longer than prescribed. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. All possible dosages and forms may not be included here. There are other drugs available to treat your condition. While you take simvastatin, your doctor will want to make sure that it isn’t affecting your liver and kidneys. Take simvastatin in the evening to maximize its effects. However, because drugs affect each person differently, we can not guarantee that this information includes all possible side effects. Simvastatin is used in adults and children who are at least 10 years old. Simvastatin oral tablet doesn’t drowsiness, but it can cause other side effects. Store the tablets between 41°F and 86°F (5°C to 30°C). Do not take simvastatin if you are pregnant. unexplained muscle weakness or tenderness, severe allergic reaction, with symptoms such as fever and trouble breathing, severe swelling of the hands, feet, and ankles, use of drugs that interact with simvastatin. Simvastatin pregnancy and breastfeeding warnings (in more detail). You may need to stop using this medicine for a short time if you have surgery or a medical emergency. Never take simvastatin in larger amounts, or for longer than recommended by your doctor. Statins are a class of drugs that lower LDL, or “bad,” cholesterol levels in the body by preventing production in the liver, where the majority of the…. Select one or more newsletters to continue. Medically reviewed by Sanjai Sinha, MD. Take simvastatin exactly as prescribed. New research shows more people can benefit from taking statins than previously believed, including people over 75 years old. Follow your doctor's dosing instructions very carefully. Available for Android and iOS devices. Simvastatin may pass into breast milk and could harm a nursing baby. muscle weakness in your hips, shoulders, neck, and back; trouble lifting your arms, trouble climbing or standing; or. Children under 10 years: Safety and efficacy not established Simvastatin is used for long-term treatment. You should always consult your doctor or other healthcare professional before taking any medication. High- Intensity (lowers LDL-C ≥ 50%) 63 40 mg ($196) 62 61 60 80mg ($9 gen, $ 236. br) 59 58 56 20 mg 54 ($196) 52 10 mg ($196) 50 40mg ($9 gen, $ 236. • Atorvastatin 10–20 mg. • Rosuvastatin 5–10 mg. • Simvastatin 20–40 mg. • Pravastatin 40–80 mg. In rare cases, simvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Take the missed dose as soon as you remember. Simvastatin comes in two forms: an oral tablet and an oral suspension. Statins Can Reduce Risk of a Heart Attack for Adults of All Ages, The 12 Best Nursery Gliders to Complete Your Baby’s Room, Providence Medicare Advantage: A Guide to Your 2021 Plan Options, Debra Sullivan, Ph.D., MSN, R.N., CNE, COI. Category X drugs should never be used during pregnancy. Uses, Benefits, and Food List, Both Red and White Meat Raise Cholesterol Levels, Study Finds, Teens’ Cholesterol Levels Improve, but Only Half Have Ideal Numbers, Hate Statins? Your doctor may occasionally change your dose to make sure you get the best results. Other drugs that increase risk of myopathy or rhabdomyolysis include: Digoxin is used to treat heart failure and arrhythmias. Simvastatin drug interactions (in more detail). These drugs block your body from breaking down simvastatin. Guidance for High-Intensity and Moderate Intensity Statin Dosing. For these people, simvastatin can increase the risk of serious liver injury. Grapefruit and grapefruit juice may interact with simvastatin and lead to unwanted side effects. Avoid eating foods that are high in fat or cholesterol. Simvastatin oral tablet is available as the brand-name drug Zocor. It comes in two forms: a tablet and a suspension. Grapefruit and grapefruit juice may interact with simvastatin and lead to potentially dangerous effects. Statins work to reduce the body’s cholesterol production. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. Using simvastatin with these drugs can increase the risk of myopathy or rhabdomyolysis. Before you start taking simvastatin, tell your doctor if you are already using any of these other medicines: heart medication - amiodarone, amlodipine, diltiazem, dronedarone, ranolazine, verapamil. If you don’t take it on schedule: Not taking simvastatin every day, skipping days, or taking doses at different times of the day may also increase your risk for high cholesterol levels, heart attack, or stroke. Crestor, which is the brand name for rosuvastatin, and simvastatin are both cholesterol-lowering drugs. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist. Having hypothyroidism or diabetes raises your risk for this condition. They won’t damage your medication. Our website services, content, and products are for informational purposes only. Simvastatin belongs to the drug class known as HMG-CoA reductase inhibitors, also called statins. Brand Name: Zocor. Copyright 1996-2020 Cerner Multum, Inc. Cholesterol production in the body is highest at nighttime. Be sure to avoid doing this when the weather is very hot or very cold. Skip the missed dose if it is almost time for your next scheduled dose. This can be harmful or prevent the drug from working well. Initial: 10-20 mg orally once/day in the evening. Zetia, atorvastatin, Jardiance, Brilinta, fenofibrate, Lopid, Xarelto, rosuvastatin, Lipitor, Crestor. Simvastatin is used to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood). Get emergency medical help if you have any of these signs of an allergic reaction to simvastatin: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Simvastatin oral tablet can interact with other medications, vitamins, or herbs you may be taking. If you’re taking both drugs, your doctor may want to monitor your digoxin level more closely. Simvastatin may interact with other medications, Important considerations for taking simvastatin, What Is Vitamin F? Simvastatin is usually taken at bedtime or with an evening meal. However, because drugs interact differently in each person, we can not guarantee that this information includes all possible interactions. Can taking simvastatin increase my risk of diabetes? Taking simvastatin with digoxin can increase levels of digoxin in your body. Do not stop taking this medicine unless your doctor tells you to. An interaction is when a substance changes the way a drug works. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Grapefruit juice can increase simvastatin levels in your body and increase the risk of side effects. For pregnant women: Simvastatin is a category X pregnancy drug. You may report side effects to FDA at 1-800-FDA-1088. They can discuss other treatment options during pregnancy. Version: 18.01. However, because of the risk of severe side effects, this drug shouldn’t be used during breastfeeding. Patients at high CHD risk: Start 40 mg/day. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine. Statins do this by blocking an enzyme in your liver to help prevent your body from making too much cholesterol. These plans provide the same coverage as…. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine. Do not use if you are pregnant or planning to become pregnant. -High-risk patients may initiate at 40 mg orally once a day. This information is not a substitute for medical advice. What is Caprylic/Capric Triglyceride and Is It Safe? Avoid grapefruit juice while taking simvastatin. If you become pregnant while taking this drug, call your doctor right away. Vitamin F is not a vitamin in the traditional sense, but a term for two important fats. In some cases, they may not be available in every strength or form as the brand-name drug. Last updated on Nov 2, 2020. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional.