“Additionally, statins lower inflammation, which we know is a factor that causes atherosclerosis and cardiovascular disease,” Dr. Laffin says. Elevated liver enzymes. Your doctor may switch you to a less-potent statin, change the dose, or explore alternative dosing strategies. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. Do Your Statins and Grapefruit Safely Mix? I think it’s very reasonable for someone who has other competing comorbidities to talk about deprescribing statins.”. Advertising on our site helps support our mission. So, if you’re over age 75 — and especially if you have other health problems — discuss the pros and cons of statin therapy with your physician, Dr. Laffin advises. “But, we know that the benefits of statins outweigh that small increase in blood glucose across multiple populations,” Dr. Laffin notes. If the numbers are similar to daily lower dose, then you should be fine going forward. This may include taking the drugs every other day or less frequently. People with diabetes ages 40 to 75 with an LDL level over 70 mg/dL and no atherosclerotic cardiovascular disease. It’s because a large body of research supports their benefits in reducing the risk of heart attack and stroke. Statins inhibit the action of an enzyme that’s responsible for cholesterol production in your liver. I have been taking statins every night for the past 5 years. Two questions I... View answer . People with an LDL cholesterol level of 190 milligrams per deciliter (mg/dL) or higher, due to a genetic condition. The drugs have become so universally used that if you haven’t been prescribed a statin already, chances are you will at some point. Should You Cancel Your Holiday Gatherings This Year Because of COVID? Policy. “If you absolutely cannot tolerate a statin at any dose, then we have other medications we can use,” such as ezetimibe (Zetia®) or newer drugs known as PCSK9 inhibitors: alirocumab (Praluent®) and evolocumab (Repatha®). Statin-related myalgias and hepatotoxicity are dose-related and so reducing systemic drug concentration may lower the incidence of ADRs and potentially increase adherence to the regimen. But yes it becomes less likely after taking it for that many years. Note: The guidelines recommend considering coronary artery calcium scoring for people at intermediate risk in whom a decision about starting statin treatment remains uncertain. (Hint: Probably Sooner Than You Think), Statins Giving You Achy Muscles? If the numbers are similar to daily lower dose, then you should be fine going forward. Mental fogginess. Certain statins — in particular, atorvastatin and simvastatin — are more likely to cause these side effects, while others, like rosuvastatin and pravastatin, have less of an effect. Change your dose. “There are good data to suggest that the more LDL lowering we can achieve, the lower the risk of adverse cardiac events such as strokes and heart attacks,” Dr. Laffin explains. Good evening. Why? Do Face Mask Brackets Work — And Are They Safe? We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. We do not endorse non-Cleveland Clinic products or services. Some types of statin should be taken in the evening. Policy. You can give a trial of stopping the drug for 3 … It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. So may consuming large quantities of grapefruit (or juice) and taking certain medications. With some perseverance, you and your physician can develop a statin regimen that works for you. If you forget to take your tablet, wait till your next dose. I am ... appointment with gastrologist for prostate examination. Our sample population was divided into two groups, one group was taking simvastatin 40 mg daily, while the other group was taking simvastatin 40 mg every alternate day. 0 comment. Cleveland Clinic is a non-profit academic medical center. Simvistatin taken every other day Pravastatin every second day Taking statin every other day Simivastin every other day Community Experts online right now. 16 Both the groups had been on statin treatment for a similar duration of time. Most statins should be taken once every 24 hours. Ask for FREE. You have successfully subscribed to our newsletter. ... What happens if 40mg simvastatin is taken every other day instead of daily does that mean it is working at the 20mg strength. We offer this Site AS IS and without any warranties. Can Niacin Be Harmful to Control Cholesterol? Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. Find everything you need to know about Zocor (Simvastatin), including what it is used for, warnings, reviews, side effects, and interactions. However, the risks and benefits of statins must be carefully considered in older populations, especially those with health problems. Cholesterol-lowering statin medications have been at the forefront of managing cardiovascular disease for several decades now. Preventive cardiologist Luke Laffin, MD, says statins lower your LDL ( or “bad”) cholesterol, which is associated with a reduced risk of atherosclerotic cardiovascular disease. Depending on the particular medication and dosage, you may need to take your statin twice a day. Non-diabetic patients ages 40 to 75 with an LDL level of 70 to 189 mg/dL and a 10-year ASCVD risk of 7.5% to less than 20% (intermediate risk) if the risk estimate and presence of certain risk-enhancing factors. They’re inexpensive and easy to obtain. Some evidence suggests that high-intensity statin therapy may help to slow, and potentially reverse, the growth of artery-clogging atherosclerotic plaques. I have heard the... View answer. Although statins all belong to the same drug class, they differ in how potent they are and how much they can lower LDL cholesterol. Just stick with one dose every other day and give your body a total rest from the medicine every other day. Can you take simvastatin every other day . Age is the most significant risk factor for atherosclerotic cardiovascular disease. Take statin every other day . Addressing these factors may ease or prevent statin-related muscle effects. Cleveland Clinic is a non-profit academic medical center. If your doctor has recommended you take a statin, here’s what you can expect. “Usually, you can find at least some dose of statin that people can tolerate, even if it is just a couple times a week,” Dr. Laffin says. For more then 25 years I have been taking statins for high ... that is supposed to help but its to soon, I have been taking it only a few days with no... View answer. Suggest dosage of Simvastatin . They may also make them less prone to rupture and cause heart attacks and strokes. In my experience, 99% of insurance companies cover at least one of them, and more than 75% cover both of them.”. However, the latest ACC/AHA guidelines recommend liver-enzyme testing only for statin users who are at higher risk or have symptoms that may suggest liver toxicity. 5 thanks. Most statins should be taken once every 24 hours. These dosage levels were taken because higher doses of simvastatin are associated with an increased risk of myopathy. MD. Overall, though, large-scale clinical trials don’t suggest an increase in cognitive problems associated with statin use, Dr. Laffin says. “It’s important to note that atorvastatin and rosuvastatin really are the workhorses of cardiology and statins at this point,” Dr. Laffin adds. In addition to more common side effects such as headache and nausea, statins occasionally may cause increases in liver enzymes, suggesting liver inflammation. Integrative suggest I consult with my cardiologist and take it every other day rather than every day.